Relationship between hepatitis B virus infection and hepatic metastasis in non-small cell lung cancer

نویسندگان

  • Fei Gao
  • Lin Jia
  • Xiaobo Du
  • Yun Wang
  • Jianjun Han
چکیده

Objective: The purpose of the study was to explore the relationship between hepatitis B virus (HBV) infection and hepatic metastasis in non-small cell lung cancer (NSCLC). Methods: Four hundred and eighty cases of NSCLC were retrospectively analyzed from January 2003 to January 2010, and the prevalence of hepatic metastasis of NSCLC in patients with and without hepatitis B virus infection were compared. Results: In the HBV carriers’ group, the prevalence of synchronous hepatic metastasis and metachronous hepatic metastasis were 13.2% and 5.9%, respectively. Meanwhile in the non-HBV group, those were 21.6% and 9.5% respectively. A significant difference between the two groups was found (P < 0.05). Conclusion: The prevalence of synchronous hepatic metastasis and metachronous hepatic metastasis in non-small cell lung cancer with HBV infection are lower than those in non-HBV infection group. Hepatic metastasis is infrequent in HBV infected cases of NSCLC.

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تاریخ انتشار 2014